Cymbalta, or duolextine, is used to treat severe depression, anxiety, diabetic nerve pain and some types of chronic pain, and can also be used to address urinary incontinence. Cymbalta is also known to have a range of side effects; in most cases these are inconvenient and cause a mild level of discomfort, however, Cymbalta is also linked to more dangerous side effects.
Nausea is the most-reported side effect in clinical trials of Cymbalta, with over one in three patients feeling queasy because of the drug.
Sleep disorders have also been linked to Cymbalta. These include insomnia, or difficulty in sleeping, and somnolence, where a patient feels tired much of the time and may need to sleep for unusually long periods of time. However, sleep disorders can also be a manifestation of the mental diseases that Cymbalta is prescribed to combat.
Around one in ten people on Cymbalta have problems with their digestive system. These can include diarrhea, constipation and the loss of appetite. In a small minority of cases, these problems extended to vomiting, indigestion and heartburn.
Headaches and dizziness affect around one in five patients prescribed Cymbalta. It should be noted that, during trials, headaches were also experienced by many of the control group who were given a placebo- the links between headaches, migraines and Cymbalta remain unclear.
Some complaints are experienced by a minority of patients; between two and five in every hundred users. These include sexual dysfunction, cold and ‘flu like symptoms including muscle pain, shakiness, headaches, a runny nose, coughing and a sore throat. Unusual side effects also include blurred vision, unusually strange or vivid dreams, and restlessness.
Discontinuing Cymbalta can have a number of severe side effects. These include increased aggression, impotence and other sexual dysfunction, depression, mania and suicidal feelings. For this reason, patients should never cease taking Cymbalta without seeking medical advice and support first. Patients often come off Cymbalta through a gradual decrease in doses over a period of weeks of months, as recommended by the manufacturer.
The role of Cymbalta in suicide cases is controversial. In adults, it appears to increase the suicide risk by around twelve per cent. The normal suicide rate of adults in America is eleven per hundred thousand, and a twelve per cent increase raises this to just over twelve per hundred thousand. The drug seems particularly problematic in relation to teenage and young adult cases, where some studies indicate the suicide risk can quadruple or more – however, no extensive research has been completed in this field. As with any drug used to treat major depression, it is difficult to discern whether many suicides have been through drug side effects, or the mental health illnesses they were intended to treat.
A very small minority of patients on Cymbalta may experience side effects that need immediate medical attention. These include anaphylactic reactions – or, in other words, extreme allergic reactions. If you or a loved one is experiencing any serious medical problem, then you should seek urgent medical attention and, if possible, take along any medication that you have been using. Other serious side effects include seizures, palpitations, hallucinations, and suicidal depression, and serotonin syndrome, which manifests itself in twitching, pupil dilation and increases heart rate.